Setiptiline Size:Solid 10 mg InChi: InChI=1S/C26H19N3O5/c1-25-26(33

InChi: InChI=1S/C26H19N3O5/c1-25-26(33

Garsetti D

It was also used in an assay where primary bovine articular chondrocytes and cartilage explants were grown in the presence of TNF-a and oncostatin M to mimic cytokine-induced damage during OA pathogenesis

assesses after 6 days) inhibits TGF-β1-mediated proliferation of familial idiopathic pulmonary arterial hypertension (iPAH) pulmonary artery smooth muscle cells (PASMCs) at an IC50 of 295 nM

10058-F4 induces cell-cycle arrest

Setiptiline Size:Solid 10 mg InChi: InChI=1S/C26H19N3O5/c1-25-26(33Setiptiline, also known as MO 8282 and teciptiline, is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). It was launched in 1989 for the treatment of depression in Japan by Mochida. Setiptiline acts as a norepinephrine reuptake inhibitor,[3] 2 adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5 HT2A, 5 HT2C, and or 5 HT3 subtypes, as well as an H1 receptor