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HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 GF 109203X inhibits collagen- and

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HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 GF 109203X inhibits collagen- andHSD1590, CAS No. 2379279 96 4, is potent ROCK inhibitor, with IC50s of 1. 22 and 0. 51 nM for ROCK1 and ROCK2, respectively. HSD1590 exhibits single digit nanomolar binding to ROCK (Kds<2 nM). HSD1590 displays low cytotoxicity. Product information CAS Number: 2379279 96 4 Molecular Weight: 359. 19 Formula: C20H18BN3O3 Chemical Name: HSD1590 Smiles: COC1C(=CC=CC=1C1=NC2=CC=C3NN=CC3=C2C2CCCC=21)B(O)O InChiKey: WTZMCUOBQPTERK UHFFFAOYSA N InChi: InChI=1S

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Description

GF 109203X inhibits collagen- and a-thrombin-induced platelet aggregation as well as collagen-triggered ATP secretion

PubMed PMID: 24500879

483(7390):479-83

6]hexacosa-1(23)

AGC activity is also dramatically decreased in AT13148-administrated HGC27 tumors

HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 GF 109203X inhibits collagen- andHSD1590, CAS No. 2379279 96 4, is potent ROCK inhibitor, with IC50s of 1. 22 and 0. 51 nM for ROCK1 and ROCK2, respectively. HSD1590 exhibits single digit nanomolar binding to ROCK (Kds<2 nM). HSD1590 displays low cytotoxicity. Product information CAS Number: 2379279 96 4 Molecular Weight: 359. 19 Formula: C20H18BN3O3 Chemical Name: HSD1590 Smiles: COC1C(=CC=CC=1C1=NC2=CC=C3NN=CC3=C2C2CCCC=21)B(O)O InChiKey: WTZMCUOBQPTERK UHFFFAOYSA N InChi: InChI=1S

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