PRI-724 - CAS# 1422253-38-0 317 AZD2014 was orally dosed to

AZD2014 was orally dosed to mice at 2

is a potent JNK inhibitor

2109424-53-3 (SAG(trans-cis) HCl)

is an allosteric inhibitor of Bcr-abl tyrosine kinase activity (IC50 = 267 nM)

2-[(E)-[(2-hydroxynaphthalen-1-yl)methylidene]amino]-N-(1-phenylethyl)benzamide

PRI-724 - CAS# 1422253-38-0 317 AZD2014 was orally dosed toPRI 724, CAS No. 1422253 38 0, also known as C 82 prodrug ICG 001 analog, is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity. Wnt signaling pathway inhibitor PRI 724 specifically inhibits the recruiting of beta catenin with its coactivator CBP (the binding protein of the cAMP response element binding protein CREB); together with other transcription factors beta catenin CBP