K-Ras G12C-IN-3 Catalog No.:M8513-10 It inhibits DNA methylation in

It inhibits DNA methylation in human cancer cell lines in vitro without detectable toxicity

2013 Oct 15

It inhibits PHD2 via binding to the 2OG binding site

Probe ML188 is a modest molecular weight SARS-CoV 3CLpro inhibitor with demonstrated antiviral activity and a non-covalent mechanism of action

a tyrosine kinase inhibitor

K-Ras G12C-IN-3 Catalog No.:M8513-10 It inhibits DNA methylation inK Ras G12C IN 3 is a novel and irreversible inhibitor of mutant K ras G12C. IC50 value: Target: K ras G12C inhibitorFor more information, please see the following patent. Heterocyclic compounds as covalent inhibitors of G12C mutant K Ras protein useful for treating cancers, and preparation thereofBy Ren, Pingda; Liu, Yi; Li, Liansheng; Feng, Jun; Wu, Tao From PCT Int. Appl. (2014), WO 2014152588 A1 20140925. Product information CAS Number: 1629268 19