CBL0137 omo-5-phenyl Salicylic Acid GSK-1120212

GSK-1120212

Eflornithine for the treatment of human African trypanosomiasis

InChiKey: CZQHHVNHHHRRDU-UHFFFAOYSA-N

2012 May 1

IP administration of SR9009 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models

CBL0137 omo-5-phenyl Salicylic Acid GSK-1120212CBL0137 (Curaxin 137) is an inhibitor of the histone chaperone FACT (facilitates chromatin transcription) that simultaneously suppresses NF B and activates p53 with EC50 of 0. 47 M and 0. 37 M, respectively. Product information CAS Number: 1197996 80 7 Molecular Weight: 336. 43 Formula: C21H24N2O2 Synonym: Curaxin 137 CBL C137 CBLC137 Chemical Name: 1,1' (9 (2 (isopropylamino)ethyl) 9H carbazole 3,6 diyl)bis(ethan 1 one) Smiles: