BV6 rase Inhibitor II JNK and H2AX activation at

JNK and H2AX activation at different times in SBcl2 cells

U87MG (brain)

Oral dosing with EPZ015666 demonstrated dose-dependent antitumor activity in multiple MCL xenograft models

This agent has been shown to inhibit tumor growth in vitro

BMC Cancer

BV6 rase Inhibitor II JNK and H2AX activation atBV6 is an inhibitor of apoptosis (IAP) proteins. It acts by promoting glioblastoma cancer stem like cell differentiation by activating NF B. Product information CAS Number: 1001600 56 1 Molecular Weight: 1205. 57 Formula: C70H96N10O8 Synonym: BV 6 BV 6 Chemical Name: (2S) 2 {[(2S) 1 [(2S) 2 cyclohexyl 2 [(2S) 2 (methylamino)propanamido]acetyl]pyrrolidin 2 yl]formamido} N {6 [(2S) 2 {[(2S) 1 [(2S) 2 cyclohexyl 2 [(2S) 2