Epirubicin - CAS# 56420-45-2 Catalog No.:M9815-2 NC(N)=N/N=C/C1=CC(/C=N/N=C(N)N)=CC=C1

NC(N)=N/N=C/C1=CC(/C=N/N=C(N)N)=CC=C1

the BET inhibitor CPI-0610 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins

on trabecular meshwork and Schlemm's canal endothelial cells

6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1

InChi: InChI=1S/C12H15N5O3

Epirubicin - CAS# 56420-45-2 Catalog No.:M9815-2 NC(N)=N/N=C/C1=CC(/C=N/N=C(N)N)=CC=C1Epirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands. Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death.