XMD8-92 Size:Solid 2 mg Smiles: NC(=O)N1CCC(CC(=O)N2CCC(CC2)[C@H]2C3=NC=C(Br)C=C3CCC3=CC(Cl)=CC(Br)=C32)CC1

Smiles: NC(=O)N1CCC(CC(=O)N2CCC(CC2)[C@H]2C3=NC=C(Br)C=C3CCC3=CC(Cl)=CC(Br)=C32)CC1

Following treatment with E7070

clemizole exhibits a sixfold selectivity for TRPC5 over TRPC4β (IC50 = 6

11 cells which express native (unmutated) FLT3

Administration of (R)-MG-132 effectively rescues the expression levels and plasma membrane localization of dystrophin

XMD8-92 Size:Solid 2 mg Smiles: NC(=O)N1CCC(CC(=O)N2CCC(CC2)[C@H]2C3=NC=C(Br)C=C3CCC3=CC(Cl)=CC(Br)=C32)CC1XMD8 92 is an ERK5 BMK1 inhibitor and also BRD4 inhibitor. XMD8 92 inhibits pancreatic tumor xenograft growth via a DCLK1 dependent mechanism. XMD8 92 blocks cellular BMK1 activation and significantly suppresses tumor growth in lung and cervical tumor models and is well tolerated in animals. Product information CAS Number: 1234480 50 2 Molecular Weight: 474. 55 Formula: C26H30N6O3 Chemical Name: 5 {[2 ethoxy 4 (4 hydroxypiperidin 1 yl)phenyl]amino}