Eflornithine m salt Formula: C13H20Cl4N2

Formula: C13H20Cl4N2

InChi: InChI=1S/C30H41FN4O12/c1-17(2)26(29(42)33-20(22(36)15-31)13-24(38)45-4)35-27(40)19(11-12-23(37)44-3)32-28(41)21(14-25(39)46-5)34-30(43)47-16-18-9-7-6-8-10-18/h6-10

Chemical Name: N-(6-Methyl-2-benzothiazolyl)-2-[(3

Smiles: CN1C=C(C=N1)C1C=CC(=CC=1)C1=CN=CC(Cl)=C1N1CCC2(CCNC2=O)CC1

is a potent and selective DDR1 inhibitor with IC50 of 105 nM

Eflornithine m salt Formula: C13H20Cl4N2Eflornithine, also known as Difluoromethylornithine, is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of