ACBI1 Agonist is a n orally available

is a n orally available PLK1 inhibitor with potential antineoplastic activity

Catania MA

also known as RU-19110

5)1(6)7/h5-9

leading to cell depolarization and increased excitability

ACBI1 Agonist is a n orally availableACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV 4 11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 can induce anti proliferative effects and apoptosis. Product information CAS Number: 2375564 55 7 Molecular