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Crizotinib Hydrochloride - CAS# 1415560-69-8 Catalog No.:M10974-2 Formula: C25H28N6O2

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Crizotinib Hydrochloride - CAS# 1415560-69-8 Catalog No.:M10974-2 Formula: C25H28N6O2Crizotinib (PF 02341066) hydrochloride (Xalkori) inhibits tyrosine phosphorylation of c Met and nucleophosmin (NPM) anaplastic lymphoma kinase (ALK) with IC50 of of 11 nM and 24 nM in cell based assays, respectively. Crizotinib hydrochloride is also a potent ROS1 inhibitor with Ki less than 0. 025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines. Product information CAS Number: 1415560 69 8

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Description

Formula: C25H28N6O2

Orexin antagonists have multiple potential clinical applications including the treatment of drug addiction

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Formula: C21H19ClN4O4

In a concentration of 128 mcg/mL Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture

Crizotinib Hydrochloride - CAS# 1415560-69-8 Catalog No.:M10974-2 Formula: C25H28N6O2Crizotinib (PF 02341066) hydrochloride (Xalkori) inhibits tyrosine phosphorylation of c Met and nucleophosmin (NPM) anaplastic lymphoma kinase (ALK) with IC50 of of 11 nM and 24 nM in cell based assays, respectively. Crizotinib hydrochloride is also a potent ROS1 inhibitor with Ki less than 0. 025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines. Product information CAS Number: 1415560 69 8

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