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ITD-1 - TGFβ inhibitor. CAS# 1099644-42-4 size:2mg solid MMAF inhibits anaplastic large cell

ITD-1 - TGFβ inhibitor. CAS# 1099644-42-4 size:2mg solid MMAF inhibits anaplastic large cell

Name: ITD-1 - TGFβ inhibitor. CAS# 1099644-42-4 size:2mg solid MMAF inhibits anaplastic large cell
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SKU: 67254103281
Price: 45.00 USD
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SKU: 67254103281

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ITD-1 - TGFβ inhibitor. CAS# 1099644-42-4 size:2mg solid MMAF inhibits anaplastic large cellITD 1, CAS No. 1099644 42 4, is a novel and highly selective TGF pathway inhibitor identified by a high throughput, embryonic stem cell (ESC) cardiac differentiation screening. ITD 1 promoted cardiomyocyte differentiation specifically via degradation of the TGF type II receptor (TGFBR2), effectively clearing the receptor from the cell surface and selectively inhibiting intracellular signaling (IC50 0. 40. 8 M), revealing a role for TGF signaling

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Description

MMAF inhibits anaplastic large cell lymphoma Karpas 299

HLY78 was used at 10-20 µM final concentration in various in vitro assays

15)16)19-11(18-7)20-4-5(3-17-20)10(21)22/h1-4H

6(9):e25264

1-dimethylethyl ester

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