SB 415286 astatin although removing Top1 was itself

although removing Top1 was itself eventually toxic

The beta3-adrenergic agonist CL316

Chemical Name: (2R)-2-{[(2S)-1-[(4R

Smiles: CC1=C(/C=C2/C3=CC(F)=CC=C3NC/2=O)NC(C)=C1C(=O)NC[C@H](O)CN1CCOCC1

106:152-168

SB 415286 astatin although removing Top1 was itselfSB 415286 is a potent and selective cell permeable, ATP competitive inhibitor of GSK3 with an IC50 value of 78 nM (similar potency for GSK3) and a Ki value of 31 nM. Pharmacological GSK 3 inhibitors are potential drugs for the treatment of neurodegenerative diseases, cancer and diabetes. Product information CAS Number: 264218 23 7 Molecular Weight: 359. 72 Formula: C16H10ClN3O5 Chemical Name: 3 [(3 chloro 4 hydroxyphenyl)amino] 4 (2 nitrophenyl) 2,5