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Cot inhibitor-1 cetic acid) PubMed PMID: 22806357

Cot inhibitor-1 cetic acid) PubMed PMID: 22806357

Name: Cot inhibitor-1 cetic acid) PubMed PMID: 22806357
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Cot inhibitor-1 cetic acid) PubMed PMID: 22806357Cot inhibitor 1 (compound 28) is a selective tumor progression loci 2 (Tpl2) kinase inhibitor with an IC50 of 28 nM. Cot inhibitor 1 shows an inhibition of TNF alpha production in human whole blood with an IC50 of 5. 7 nM. Product information CAS Number: 915365 57 0 Molecular Weight: 553. 46 Formula: C27H27Cl2FN8 Chemical Name: 6 [({1 [2 (azepan 1 yl)ethyl] 1H 1,2,3 triazol 4 yl}methyl)amino] 8 chloro 4 [(3 chloro 4 fluorophenyl)amino]quinoline 3

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PubMed PMID: 22806357

CC1=CN=C(C[S@@](=O)C2[N-]C3=CC=C(C=C3N=2)OC)C(C)=C1OC

26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16

5 MTD dose of Bortezomib (0

110(21):3372-7

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