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Altered SOD1 maturation and post-translational modification in amyotrophic lateral sclerosis spinal cord

Firstly, when comparing the reduction of GSSG to GSH by glutathione reductase and the oxidation of GSH to GSSG by glutathione peroxidase, the reaction catalyzed by glutathione reductase was more efficient

Additionally, observational studies linking midazolam to adverse neurological outcomes often overlook confounding factors such as illness severity, ventilatory instability, and concurrent opioid use, making causal inference uncertain (106, 262)

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