Dabrafenib - CAS# 1195765-45-7 size:10mg solid Precision Oncology for Hepatocellular Cancer:

Precision Oncology for Hepatocellular Cancer: Slivering the Liver by FGF19-FGF4-KLB Pathway Inhibition

PubMed PMID: 29304833

correlates with CK2α mRNA and protein levels but not the CK2α' catalytic subunit

named after the polo gene of Drosophila melanogaster

Blachly JS

Dabrafenib - CAS# 1195765-45-7 size:10mg solid Precision Oncology for Hepatocellular Cancer:Dabrafenib, CAS No. 1195765 45 7, also known as GSK2118436 , is an orally bioavailable inhibitor of B raf (BRAF) protein with potential antineoplastic activity. Dabrafenib selectively binds to and inhibits the activity of B raf, which may inhibit the proliferation of tumor cells which contain a mutated BRAF gene. B raf belongs to the the raf mil family of serine threonine protein kinases and plays a role in regulating the MAP kinase ERKs signaling