Pomalidomide 4-alkylC7-amine - CAS# 2446474-05-9 Catalog No.:M7204-2 PF 4457845

PF 4457845

PubMed Central PMCID: PMC5576570

with an IC50 of ∼17 nM

CX-6258 causes dose dependent inhibition of the phosphorylation of two pro-survival proteins

This drug may represent an additional therapeutic paradigm for the treatment of XFG

Pomalidomide 4-alkylC7-amine - CAS# 2446474-05-9 Catalog No.:M7204-2 PF 4457845Pomalidomide 4 alkylC7 amine, CAS No. 2446474 05 9, Cereblon ligand with alkyl linker and terminal amine for onward chemistry Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC7 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. Product information CAS Number: 2446474 05 9 Molecular Weight: 422. 91