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Zatebradine Catalog No.:M8447-2 Chemical Name: gadolinium(III) 2

SKU: 86494824987

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Zatebradine Catalog No.:M8447-2 Chemical Name: gadolinium(III) 2Zatebradine (UL FS 49 (free base); UL FS 49CL (free base)) is a potent inhibitor of hyperpolarization activated cyclic nucleotide gated (HCN) channels with an IC50 value of 1. 96 M. Zatebradine blocks the slow inward current through human HCN1, HCN2, HCN3 and HCN4 channels, with IC50 values of 1. 83 M, 2. 21 M, 1. 90 M and 1. 88 M, respectively. Product information CAS Number: 85175 67 3 Molecular Weight: 456. 57 Formula: C26H36N2O5 Synonym: UL FS49

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Description

Chemical Name: gadolinium(III) 2

It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1)

PubMed PMID: 26185454

InChi: InChI=1S/C28H34O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-7

6)25(31)16(3)24(14)30/h10

Zatebradine Catalog No.:M8447-2 Chemical Name: gadolinium(III) 2Zatebradine (UL FS 49 (free base); UL FS 49CL (free base)) is a potent inhibitor of hyperpolarization activated cyclic nucleotide gated (HCN) channels with an IC50 value of 1. 96 M. Zatebradine blocks the slow inward current through human HCN1, HCN2, HCN3 and HCN4 channels, with IC50 values of 1. 83 M, 2. 21 M, 1. 90 M and 1. 88 M, respectively. Product information CAS Number: 85175 67 3 Molecular Weight: 456. 57 Formula: C26H36N2O5 Synonym: UL FS49

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