WAY-316606 hydrochloride - Secreted Frizzled-related Protein-1 (sFRP-1) Inhibitor. CAS# 1781835-02-6 0035 Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2

Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2

It inhibits the interaction between β-catenin and T cell factor 4 (Tcf4) in quantitative reporter assays of β-catenin/Tcf4 binding (Ki = 53

Aticaprant

It inhibits vascular smooth muscle cell inflammation and migration as well as promotes adipocyte differentiation and regulates adipose cell function in vivo

34(10):2021-38

WAY-316606 hydrochloride - Secreted Frizzled-related Protein-1 (sFRP-1) Inhibitor. CAS# 1781835-02-6 0035 Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2WAY 316606, CAS No. 1781835 02 6, is a novel potent and selective inhibitor of secreted frizzled related protein 1 (sFRP 1) with an IC50 ~ 0. 65 M. WAY 316606 prevents sFRP 1 from interacting with Wnt and thus increases Wnt signaling. WAY 316606 can increase total bone area in a murine calvarial organ culture assay. Product information CAS Number: 1781835 02 6 Molecular Weight: 484. 94 Formula: C18H20ClF3N2O4S2 Related CAS Number: 915759 45 4 (free