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AAE-581 - CAS# 354813-19-7 Catalog No.:M60434-10S 1152/ajpcell

AAE-581 - CAS# 354813-19-7 Catalog No.:M60434-10S 1152/ajpcell

Name: AAE-581 - CAS# 354813-19-7 Catalog No.:M60434-10S 1152/ajpcell
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SKU: 96387943831
Price: 35.00 USD
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SKU: 96387943831

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AAE-581 - CAS# 354813-19-7 Catalog No.:M60434-10S 1152/ajpcellBalicatib(AAE 581), CAS No. 354813 19 7, is a potent and selective inhibitor of cathepsin K; 10 100 fold more potent in cell based enzyme occupancy assays than against cathepsin B, L, and S. IC50 value: Target: cathepsin K The cathepsin K inhibitor AAE 581 (balicatib) as the most advanced of them passed Phase II clinical trials in 2005. Eighty adult female Macaca fascicularis underwent bilateral ovariectomies and were dosed twice daily by oral gavage

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Description

1152/ajpcell

17328-16-4

3H)-pyrimidinedione

57µM for HDAC1

2-PMPA at 250 mg/kg

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