Bay 60-7550 - CAS# 439083-90-6 Size:Solid 10 mg STF-62247 also leads to cell

STF-62247 also leads to cell death by increasing acidification and inducing autophagy in VHL-deficient cells

Formula: C47H80O17

Smiles: CN1N=CC2=C1N=C(N)N=C2N1CCN(C[C@@H]1C)C(=O)NC1=CC=C(C=C1C)OC

oral aministration of PD173074 blocks tumor growth similar to that seen with single-agent cisplatin administration

Smiles: CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CC1C=CC=CC=1)C(O)=O

Bay 60-7550 - CAS# 439083-90-6 Size:Solid 10 mg STF-62247 also leads to cellBAY 60 7550 is a potent PDE2 inhibitor with IC50 values of 2. 0 nM (bovine) and 4. 7 nM (human). BAY 60 7550 antagonizes oxidative stress induced anxiety like behavioral effects in mice by increasing cGMP signaling. Phosphodiesterases (PDEs) are key regulatory enzymes of intracellular cAMP cGMP levels. These second messengers play important regulatory roles in controlling steroidogenesis in the adrenal. Disruption of PDEs has been associated with a