Sodium Channel inhibitor 1 henicol (-)-Huperzine A is more potent

(-)-Huperzine A is more potent than tacrine

inhibits the activation of nuclear factor-κB

5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide

10-100 fold more potent in cell-based enzyme occupancy assays than against cathepsin B

and tumor necrosis factor-α (TNF-α))

Sodium Channel inhibitor 1 henicol (-)-Huperzine A is more potentSodium Channel inhibitor1, one of 3 Oxoisoindoline 1 carboxamides, is a novel and selective voltage gated sodium channel for pain treatment. IC50 Value: 0. 16 uM ( Na v1. 7, V hold 90mV); 0. 41 uM (Na v1. 7, V hold 90mV) Target: Na v1. 7Sodium Channel inhibitor1 demonstrated concentration dependent efficacy in preclinical behavioral pain models. Product information CAS Number: 1198117 23 5 Molecular Weight: 473. 42 Formula: C24H19F4N3O3 Chemical Name: