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ADA33 Polyclonal Antibody, 20ul ADME Alternative splicing leads to variants

SKU: 61408094894

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ADA33 Polyclonal Antibody, 20ul ADME Alternative splicing leads to variantsThis gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell cell and cell matrix interactions including fertilization muscle development and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial

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Description

Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region

L-Asp substrates are subsequently conjugated to L-Arg| which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome

7 kb and is expressed predominantly in adult and fetal brain whereas the smaller transcript of approximately 10

It functions as the main mediator of VEGF-induced endothelial proliferation

Inducible expression of IRF7 is largely restricted to lymphoid tissue

ADA33 Polyclonal Antibody, 20ul ADME Alternative splicing leads to variantsThis gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell cell and cell matrix interactions including fertilization muscle development and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial

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