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Trk B(Phospho Tyr516) Polyclonal Antibody, 20ul Mini dry bath HDAC7 is orthologous to mouse

SKU: 6261691240

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Trk B(Phospho Tyr516) Polyclonal Antibody, 20ul Mini dry bath HDAC7 is orthologous to mouseThis gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

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Description

HDAC7 is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT

belongs to the POTE family

Interacts with the phosphorylated carboxyterminal domain of POLR2A

This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits| and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation

This gene has pseudogenes on chromosomes 20 and 22

Trk B(Phospho Tyr516) Polyclonal Antibody, 20ul Mini dry bath HDAC7 is orthologous to mouseThis gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

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